can you take tmg and dmg at the same time period

in nutritional sciences from the University of Connecticut-brought up a concern about overdosing on NAD+ boosters: high doses of NMN or NR can interfere with DNA methylation. In an interview with Peter Attia, MD, Chris Masterjohn-who has a Ph.D. It may be too early to untangle the interconnections between NAD+ supplementation and DNA methylation, but skeptics already question the benefits of high dose NMN and NR. To prolong your health during aging, the goal is to turn on longevity genes and turn off disease-causing genes. Methylation is one way to control gene expression, turning genes off and on as needed. But not all genes are active all the time. Methylation adds methyl groups to DNA, reworking a gene’s function. As we age, DNA methylation gets reprogrammed by what researchers call the “epigenetic clock.” For example, in older people, the immune system is weaker, but autoimmunity becomes more active. In some tissue, there is too much methylation and in others not enough.

During aging, the genome erodes, and methylation patterns degrade. And, DNA methylation plays a crucial role in aging.Īge-associated DNA methylation is a new field of study. Methylation neutralizes hormones, manages neurotransmitters, and plays a key role in energy production and immune function. Having enough NAD+ and maintaining methylation are necessary for health, energy, and longevity. Can NAD+ supplements interfere with methylation pathways? If so, what does that mean for your health? Will you live longer but increase your disease risk? Are there ways to boost NAD+ and support methylation for healthy longevity?

Can you take tmg and dmg at the same time period